AYYAVOO, VELPANDI,NAGASHUNMUGAM, THANADAVARAYAN,WEINER, DAVID B.
申请号:
DK08075892
公开号:
DK2044950T3
申请日:
1998.09.18
申请国别(地区):
DK
年份:
2012
代理人:
摘要:
The present invention is directed to nucleic acid molecules encoding attenuated, non-functional virion infectivity factor ( vif ) proteins. The nucleic acid molecules of the invention are inserted into recombinant expression vectors and administered to mammals in order to induce a cellular and humoral immune response to the encoded protein product.