PENGLIE ZHANG,ANDREW M. K. PENNELL,JOHN J. KIM WRIGHT,WEI CHEN,MANMOHAN R. LELETI,YANDONG LI,LIANFA LI,YUAN XU
申请号:
PT06773773
公开号:
PT1906965E
申请日:
2006.06.22
申请国别(地区):
PT
年份:
2015
代理人:
摘要:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.