PENNELL ANDREW M. K.,WRIGHT J J KIM,SEN SUBHABRATA,CHEN WEI,DIARAGHII DANIEL JOSEPH,ZHANG PENGLIE,AGGEN JAMES B
申请号:
IN2674/KOLNP/2006
公开号:
IN261862B
申请日:
2006.09.14
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
Compounds are provided that act as potent modulators of one or more of the CCR1, CCR2 and CCR3 receptors. The compounds are generally fused-, spiro- or bridged-nitrogen heterocycles having an aryl and heteroaryl component and are useful in pharmaceutical compositions, methods for the treatment of CCR1-, CCR2- and/or CCR3-mediated diseases, and as controls in assays for the identification of competitive receptor antagonists for the above chemokine receptors.