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IMPROVED DEPOT FORMULATIONS�
专利权人:
发明人:
WRIGHT JEREMY C,THEEUWES FELIX,GIBSON JOHN W,BRANHAM KEITH E,SJOBECK STEFANIA
申请号:
IN201718003726
公开号:
IN201718003726A
申请日:
2017.02.01
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
Disclosed are formulations and related methods that comprise a non- polymeric, non-water soluble high viscosity liquid carrier material having a viscosity of at least 5,000 cP at 37°C that does not crystallize neat under ambient or physiological conditions a specified linear polymer comprising lactide repeat units and one or more solvents that have a solvent capacity. Preferably the formulations contain sucrose acetate isobutyrate (SAIB), poly(lactide-c glycolide) (PLGA) and a suitable solvent, being preferably NMP. Exemplified drugs ar risperidone and naltrexone.
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