GOVINDAPPA, NAGARAJ,SOARES, MARIA MELINA,SASTRY, KEDARNATH
申请号:
CA2902830
公开号:
CA2902830A1
申请日:
2014.03.10
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention relates generally to the field of generating recombinant chimeric fusion proteins to be used in the cancer therapy, and more specifically, to fusion molecules of Anti- EGFRl-TGFßRII, Anti-EGFR1-PD1 and Anti-CTLA4-PD1 and methods of generating same, wherein the methods reduce production costs and increase homogeneity of the recombinant chimeric fusion proteins.