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Antibacterial compounds
专利权人:
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
发明人:
CAPEZZONE DE JOANNON, ALESSANDRA,MANGANO, GIORGINA,FURLOTTI, GUIDO,GAROFALO, BARBARA,MAGARO, GABRIELE,OMBRATO, ROSELLA
申请号:
ARP170101555
公开号:
AR108778A1
申请日:
2017.06.07
申请国别(地区):
AR
年份:
2018
代理人:
摘要:
Claim 1: a formula compound (1): a-l-1-y-l2-r-b (1), wherein a is a circulating group with one formula,(3) And (4),en las que G es CH o N G es CR o N G es CH o N cuando la l nea discontinua representa un doble enlace o CHNH u, when the dotted line represents a simple link; g830808, when the dotted line represents a double link, that is, ch or N;NH u o when the dotted line represents a simple link; C1 represents the atom needed to form a six member secretory or aromatic cycle, which selectively includes one or more heteromorphic atoms selected from nitrogen and oxygen atoms, 2. Replaced by one or more substitutes selected from the halogen group, tar group c833213;grupo ciano grupo oxo (3DO)and C₁₋₃ alkoxy group;R1 is hydrogen atom, halogen atom, Ciano or alcoxi c83223 group;L¹ is a bond s, or C₁₋₃ alkylene group,optionally substituted with hydroxy group; Y is a ring selected from the group consisting of a piperidinyl, piperazinyl, pyrrolidinyl, 1-3 cyclobutyl, 1-3 cyclopentyl, 1-2 cyclopropyl, azetidinyl, azabicyclo-octyl, morpholinyl and cyclohexyl ring, said ring being optionally substituted with one or more substituents selected from the group consisting of hydroxy group, C₁₋₃-alkylenyl group, C₁₋₃-O-C₁₋₃ alkyl group,Lease Group No. c83218c83331-83323-conr'r, And Connor's "R" teamin which R ’and R’ ’are hydrogen atom or C₁₋₃ alkyl;LZ is S-type connection, group asphalt c833218331;NR group NR group ’’ - Cquile alkylene,C₁₋₃-NR ’’ alkyl group,NR group" - c8332131-832331-nr ',or C₁₋₃-NR ’’ ’- Cil alkylene group,said group being optionally substituted with a hydroxy group, in which R ’’ is hydrogen, C₁₋₃ alkyl,C₁₋₃-OH alkylene, C₁₋₃-O-C₁₋₃ alkyl,o alquilenil C -CONR Ra. R 'and R' are a hydrogen atom or c83231 / 8323;R is a heterocycle, shunt or aromatic link or ring composed of five members, which contains one or more nitrogen atoms. You can choose ch8322; "Oh, ch8322;" CN, CN or conr'r ',a. R 'and R' are a hydrogen atom or c83231 / 8323;B is a periodic group with
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