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USE OF STEM CELLS TO REDUCE LEUKOCYTE EXTRAVASATION
专利权人:
ABT HOLDING COMPANY
发明人:
WODA, JULIANA,VAN'T HOF, WOUTER
申请号:
SG10201913624Y
公开号:
SG10201913624YA
申请日:
2010.07.21
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
The invention is generally directed to reducing inflammation by means of cells that secrete factors that reduce leukocyte extravasation. Specifically, the invention is directed to methods using cells that secrete factors that downregulate the expression of cellular adhesion molecules in vascular endothelial cells. Downregulating expression of cellular adhesion molecules reduces leukocyte adhesion to the endothelial cells such that extravasation is reduced. The end result is a reduction of inflammation. The cells are non-embryonic non-germ cells that have pluripotent characteristics. These may include expression of pluripotential markers and broad differentiation potential.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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