高成型性、高流動性低置換度ヒドロキシプロピルセルロースおよびそれを含む固形製剤
- 专利权人:
- 信越化学工業株式会社
- 发明人:
- 丸山 直亮,小久保 宏恭
- 申请号：
- JP2009103871
- 公开号：
- JP5324302B2
- 申请日:
- 2009.04.22
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要：
To provide low substitution hydroxypropyl cellulose having improved moldability and flowability and usable without being restricted in addition amount.
SOLUTION: The method for producing a low substitution hydroxypropyl cellulose powder includes at least: a process for compaction-grinding low substitution hydroxypropyl cellulose having a substitution molar number of 0.1-0.4 per anhydrous glucose unit and which is obtained by etherifying alkali cellulose and a classification process for obtaining the low substitution hydroxypropyl cellulose powder having an average particle diameter of 20-50 &mu m, a 90% cumulative particle diameter of 50-100 &mu m, and a ratio of the 90% cumulative particle diameter to the average particle diameter (90% cumulative particle diameter/average particle diameter) of &le 2.4 by treating the compaction-ground low substitution hydroxypropyl cellulose with a pneumatic classifier.
COPYRIGHT: (C)2011 and JPO& INPIT
- 来源网站：
- 中国工程科技知识中心
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