Robert K. PRUD'HOMME,Kurt D. RISTROPH,Nathalie M. PINKERTON,Hoang D. LU,Paradorn RUMMANEETHORN
申请号:
US16761140
公开号:
US20200268679A1
申请日:
2018.11.02
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Methods for encapsulating water-soluble biologic and small molecule active pharmaceutical ingredients (APIs) into nanoparticles by applying nanoprecipitation techniques and ion-pairing the nanoparticles with hydrophobic counterions to produce new API salts that exhibit altered solubilities are presented.