13,13-Dimethyl-des-C,D analogs of 1alpha, 25-dihydroxy-19-nor-vitamin D3 compounds and topical composition dosage forms and methods of treating skin conditions

• 收藏
• 分享

专利权人:

Wisconsin Alumni Research Foundation

发明人:

Deluca, Hector F.,Sicinski, Rafal R.,Plum, Lori A.,Nieves, Nirca J.,Clagett-Dame, Margaret,Plonska-Ocypa, Katarzyna,Grzywacz, Pawel

申请号：

AU2009206449

公开号：

AU2009206449B2

申请日:

2009.01.22

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

13,13-Dimethyl-flfes-C,D analogs of lα,25-dihydroxy-19-nor-vitamin D3 compounds and topical composition dosage forms thereof, and methods of treating skin conditions thereof. Exemplary active pharmaceutical ingredients include (lR,3R)-5-[(E)-(S)-11'-hydroxy-5',5',7',11'-tetramethyl-dodec-2'-enylidene]-2-metylene-cyclohexane-l,3-diol, (lR,3R)-5-[(Z)-(S)-11 '-hydroxy-5',5',7',11'-tetramethyl-dodec-2'-enylidene]-2-metylene-cyclohexane-l,3-diol, (lR,3R)-5-[(E)-(R)-l 1 '-hydroxy-5',5',7',11 '-tetramethyl-dodec-2'-enylidene]-2-metylene- cyclohexane-l,3-diol, and lR,3R)-5-[(Z)-(R)-11'-hydroxy-5',5',7',11'-tetramethyl-dodec-2'- enylidene] -2-metylene-cyclohexane- 1,3 -diol.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/