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MODIFIED DOUBLE-STRANDED POLYNUCLEOTIDE
专利权人:
DAIICHI SANKYO COMPANY; LIMITED
发明人:
KOIZUMI, MAKOTO,HIROTA, YASUHIDE
申请号:
EP10826845
公开号:
EP2495323A4
申请日:
2010.10.29
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention provides a double-stranded polynucleotide having a sense strand polynucleotide consisting of a nucleotide sequence complementary to a target sequence in a target gene, and an antisense strand polynucleotide having a nucleotide sequence complementary to the sense strand polynucleotide, wherein an aryl or heteroaryl compound is bound to a phosphate group at the 5-end of the antisense strand polynucleotide.
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中国工程科技知识中心
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