A method of treating a skin disorder (e.g., an inflammatory or neoplastic skin disorder) in a subject in need thereof is carried out by administering (e.g., topically administering) the subject an active agent in a treatment effective amount. The active agent may be a compound of Formula I: wherein: each R is independently selected substituted or unsubstituted aryl, heteroaryl, cycloalkyl, or heterocycloalkyl； each A is an independently selected hydrogen, an electron-withdrawing group, or electron donating group； M is a metal； and Z− is a counterion； or a pharmaceutically acceptable salt thereof.
