Ledbetter, Jeffrey A.,Grosmaire, Laura Sue,Thompson, Peter Armstrong,Simon, Sandy Alexander,Brady, William,Hayden-Ledbetter, Martha Susan
申请号：
AU2006272555
公开号：
AU2006272555B2
申请日:
2006.07.25
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present application generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The application further provides materials and methods for application treatment of diseases involving aberrant B-cell activity. In addition, the application provides humanized CD37-specific binding molecules.
