A handle 1 for controlling instruments, includes a frame 2 with a center line 9, operating elements 4, 10, 24 that are connected to the frame 2, which operating elements 4, 10, 24 are movable between a first and a second position, an actuator element 6 that is controllable by the operating elements 4, 10, 24, which actuator element 6 is constructed and arranged for controlling an instrument 53 that is arranged at a distance from the handle 1. The operating elements 4, 10, 24 are arranged in a rotationally symmetric configuration that is concentric with the center line 9 of the frame 2. An endoscopic instrument 60 including a tube like element 50, a tool 53 and a handle 1, and an assembly 80 including an endoscopic instrument 60 and an endoscope 70 are also described.