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COMPOSITIONS AND METHODS COMPRISING BINDING PROTEINS FOR ADALIMUMAB
专利权人:
发明人:
Zehra Kaymakcalan,Limin Xiong
申请号:
US14630322
公开号:
US20150166678A1
申请日:
2015.02.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Compositions and methods comprising proteins that bind specifically to adalimumab are disclosed herein. Adalimumab is a monoclonal antibody specific for the cytokine TNF-α and was developed to treat TNF-α mediated inflammatory diseases. In one aspect of the instant invention, the binding proteins are antibodies directed toward adalimumab. These antibodies, including binding fragments thereof, can be used in a clinical setting as well as for research and development. For example, these anti-adalimumab antibodies can be employed to neutralize adalimumab.
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