THE GEORGE WASHINGTON UNIVERSITY;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC
发明人:
Haitao CUI,Lijie Grace ZHANG,Yimin HUANG
申请号：
US16845329
公开号：
US20200316254A1
申请日:
2020.04.10
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A cardiac patch for treatment of a mammalian heart including perfusable vessels embedded integratedly between two layers of anisotropically oriented myocardial fibers. The cardiac patch is made using a dual 3D bioprinting technique using stereolithography to form an anisotropic construct and extrusion printing to form perfusion vessels. A nutrient and oxygen containing media can be provided within the perfusion vessels for growth of cells in the cardiac patch. The technique permits larger patches to be made for the treatment of cardiac damage in both small and large mammalian hearts.
