מלח טוזילאט של (5–(9r, 8s–פלואורו–8–(4–פלואורופניל)–9–(1–מתיל–4,2,1–1h– טריאזול–5–יל)– 9,8– דיהידרו–2h–פירידו[2,3,4–דה] פתאלאזינ–3(3h)

专利权人:: Medivation Technologies LLC;BIOMARIN PHARMACEUTICAL INC.;MEDIVATIONS INC.

摘要：: Provided herein are (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt forms, including crystalline forms, and methods of their preparation. Pharmaceutical compositions comprising a (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt are also provided, as are methods of using (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate salt to treat a disease or condition, such as a cancer.