The Brigham and Women's Hospital, Inc.;Massachusetts Institute of Technology;Novo Nordisk A/S
发明人:
Alex G. Abramson,Morten Revsgaard Frederiksen,Brian Jensen,Mikkel Oliver Jespersen,Carlo Giovanni Traverso
申请号：
US16691579
公开号：
US20200129441A1
申请日:
2019.11.21
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface. The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage with a surface. In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components.
