AHMAD KHODABOCUS,ZHI HUI LU,CHRIS HUGH SENANAYAKE,HANXUN WEI,YONGDA ZHANG
申请号：
IN1882/DELNP/2014
公开号：
IN2014DN01882A
申请日:
2014.03.12
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
Disclosed are processes for making 2, 3 disubstituted indole compounds such as compounds of general formula I comprised of the steps of a) reacting a bromoindole compound (i) with a dialkoxyl C1-5 borane in the presence of a ligand, a palladium catalyst and a base to make a compound of general formula (ii) or alternatively reacting compound (i) with a trialkyl magnesiate reagent, followed by treatment with a borate b) reacting the product of step a with a R2-Hal where R2-Hal is defined herein.
