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COMPOSITION STABLY CONTAINING SINGLE-STRANDED NUCLEIC ACID MOLECULE THAT SUPPRESSES EXPRESSION OF TGF-BETA1 GENE
专利权人:
BONAC CORPORATION;Hirofumi TAKEUCHI
发明人:
Taimu YAMADA,Hidekazu TOYOFUKU,Kohei TAHARA,Risako ONODERA,Hirofumi TAKEUCHI
申请号:
US15771305
公开号:
US20180339064A1
申请日:
2016.10.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides a composition containing a single-stranded nucleic acid molecule consisting of a nucleotide sequence shown by 5′-AGCAGAGUACACACAGCAUAUACC-P-GGUAUAUGCUGUGUGUACUCUGCUUC-P-G-3′ (SEQ ID NO: 1) (in the sequence, P is a proline derivative linker represented by (I) in the DESCRIPTION) and a buffer, and having the following features:(a) being in the form of a solution at ambient temperature; and(b) a content of the nucleic acid molecule after storage at 25° C., relative humidity 60% for 4 weeks, of not less than 80% relative to the content at the time of start of the storage.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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