Methods for the synthesis of various novel substituted dipeptide derived nitrogen-containing heterocyclic compounds and their pharmaceutically acceptable salt derivatives are provided. The compounds of the invention are useful as medicaments for the treatment or prevention of disease in a mammal, for example a human. In particular the compounds are useful as immunotherapeutics and anti-microbial drugs or vaccines. These heterocyclic derivatives can be used as an active agent in a pharmaceutical, as well as a diagnostic utility.Methods for the synthesis of various novel substituted dipeptide derived nitrogen-containing heterocyclic compounds (I) and their pharmaceutically acceptable salt derivatives are provided. The compounds of the invention are claimed and are useful as medicaments for the treatment or prevention of disease in a mammal, for example a human. In particular the compounds are useful as immuno therapeutics and anti -microbial drugs or vaccines. These heterocyclic derivatives can be used as an active agent in a pharmaceutical, as well as a diagnostic utility.Linvention concerne des méthodes destinées à la synthèse de divers nouveaux composés hétérocycliques (I) contenant de lazote dérivés de dipeptides substitués ainsi que leurs dérivés de sels de qualité pharmaceutique. Ces composés sont utiles comme médicaments pour le traitement ou la prévention dune maladie chez un mammifère, tel quun être humain. Plus particulièrement, ces composés sont utiles comme agents immunothérapeutiques et comme médicaments ou vaccins antimicrobiens. Ces dérivés hétérocycliques peuvent être utilisés comme un agent actif à des fins pharmaceutiques et diagnostiques.
