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SILICON BASED CYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING MALARIA AND TOXOPLASMOSIS
专利权人:
发明人:
DUMBALA SRINIVASA REDDY,DHANASEKARAN SHANMUGAM,REMYA RAMESH,ANURAG SHUKLA,MEENAKSHI ANIL BELEKAR
申请号:
IN201611005767
公开号:
IN201611005767A
申请日:
2016.02.19
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention discloses novel silicon incorporated cyclic compounds of formula I, tf R2 \ / 0 Ar1 \ r 2 I Wherein Ar and Ar are individually selected from any aryl group which can be optionally substituted X is selected from any inorganic anion such as halide, carbonate, sulfate, nitrate or any organic anion selected from acetate, tartarate, citrate, carbonate or organosulfonates such as tosylate, mesylate, triflate R and R are individually selected from C1-C8 alkyl, cycloalkyl, aryl, heteroaryl, aralkyl, alkoxyalkyl, aminoalkyl, thioalkyl, haloalkyl or hydroxyalkyl. R and R together may form a ring which optionally may be substituted or may contain heteroatoms a pharmaceutical composition comprising a therapeutically effective amount of compounds of general formula I, including geometrical isomers and/or salts thereof along with a drug and optionally along with a carrier or diluent or pharmaceutically acceptable excipient for treating malaria and toxoplasmosis.
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