Tetrahydro[1,8]naphthyridine sulfonamide and related compounds for use as agonists of RORy and the treatment of disease

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专利权人:

Lycera Corporation

发明人:

Aicher, Thomas Daniel,Toogood, Peter L.,Hu, Xiao

申请号：

AU2013259624

公开号：

AU2013259624A1

申请日:

2013.05.08

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The invention provides tetrahydro[1,8]naphthyridine and related compounds, methods of promoting RORy activity and/or increasing the amount of iL-17 in a subject, and therapeutic uses of the tetrahydro[1,8]naphthyridine and related compounds. In particular, the invention provides sulfonamide-tetrahydro[1,8]naphthyridine and related compounds, methods of using such compounds to promote RORy activity and/or increase the amount of iL-17 in a subject, and treat medical conditions in which activation of immune response would be beneficial such as in cancer and infections.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/