MODULATION OF IMMUNE RESPONSE USING BTLA AGONIST ANTIBODIES

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专利权人:

SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE

发明人:

Carl F. WARE,John SEDY,Paula NORRIS

申请号：

US15570013

公开号：

US20180155426A1

申请日:

2016.04.29

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention relates to the seminal discovery that BTLA agonist antibodies modulate the immune system. Specifically, the present invention provides antibodies which bind BTLA in the activated state enhancing BTLA signaling. The present invention further provides methods of treating immune and inflammatory diseases and disorders with a BTLA agonist antibody.

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