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downstream flow controlled organ perfusion apparatus
专利权人:
LIFELINE SCIENTIFIC; INC.
发明人:
BRIAN L. OTTS,CHRISTOPHER P. STEINMAN,DAVID KRAVITZ,JEFFREY S. LOUIS,MATTHEW COPITHORNE,PETER DEMUYLDER
申请号:
BR112015000496
公开号:
BR112015000496A2
申请日:
2013.07.08
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
abstract: (a) a method of perfusing an organ (20) includes connecting at least two tubes to the organ, applying a fluid motive force to a perfusion fluid in the two tubes to force the fluid through the two tubes into the organ, and perfusing the organ through at least two tubes such as the fluid motive force, provided by eg a pump (80), and backpressure generated by the organ, establishes a flow balance between at least two tubes. the flow balance may be altered without altering the fluid motive force that is applied, e.g. by flow control clamps (127, 137), such as pinch valves. a detector may be provided to detect the presence of an optional component, wherein the perfusion apparatus (10) is controlled based on a first mode of operation when the component is detected, and a second mode when the component is not detected. abstract of the patent abstract: "downstream flow controlled organ perfusion apparatus". It is a method of perfusing an organ (20) which includes connecting at least two tubes to the organ, applying a fluid driving force to an infusion fluid in the two tubes to force fluid through the two tubes into the tube. perfusion of the organ through the at least two tubes so that the fluid driving force provided by, for example, a pump (80) and the back pressure generated by the organ establishes a flow balance between the at least minus two tubes. The flow balance can be changed without changing the fluid driving force that is applied, for example, through flow control clamps (127, 137), such as handle valves. A detector may be provided for detecting the presence of an optional component, wherein the perfusion apparatus (10) is controlled based on a first mode of operation when the component is detected and a second mode when the component is not detected.abstract: (en)a method of perfusing an organ (20) includes connecting at least two tubes to the organ, applying a fluid motive force to a perfusion fluid in the two tubes to force the fluid through the two
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