The apparatus comprises a conveyor defining a path for transporting a device along the path； and a plurality of modules including at least one of (i) a de-contamination station located on the conveyor path and configured to receive therein the device and de-contaminate at least a surface of the device； (ii) a filling station located on the conveyor path downstream of the de-contamination station and including at least one filling or injection member that is in fluid communication with a source of substance to be filled into a chamber of the device； and (iii) a sealing station located on the conveyor path downstream of the filling station for sealing the filled device. The plurality of modules are (a) in series with each other, and/or (b) in parallel with each other, and are configured to permit addition of additional modules in series or in parallel with said plurality of modules.멸균 충전을 위한 장치 및 방법은, 바늘 침투 가능한 격막 및 바늘 침투 가능한 격막과 유체 통신하는 밀봉된 챔버를 포함하는 디바이스의 바늘 침투 가능한 표면 표면을 오염제거하는 것을 포함한다. 충전 바늘은 바늘 침투 가능한 격막을 침투하고, 충전 바늘을 통해 그리고 챔버 내로 물질을 도입하고, 결국 격막으로부터 빠진다. 액체 밀봉제가 격막의 침투된 영역에 도포된다. 방사 또는 에너지가 액체 밀봉제에 적용되어 액체 상태로부터 고체 상태로 액체 밀봉제를 경화한다.
