BEASLEY, MATTHEW DAVID,NIVEN, KEITH PHILIP,KIEFEL, BEN ROSS
申请号:
EP12824386
公开号:
EP2744931A4
申请日:
2012.08.17
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates generally to polypeptides, such as antibody sample molecule, show high stability and solubility. It particularly, include the fields VL and VH that the pairing of soluble expression and folding is shown in reduction or intracellular environment the present invention relates to polypeptide. To polypeptide as the polynucleotides of the library of such polypeptide or polynucleotides the invention further relates to coding, to the method for using such polypeptide under study for action, diagnosis and therapeutic applications.