Julie Kan,Stuart Thomson,Gretchen M. Argast,Matthew E. OConnor,Murray Robinson,Bin Feng,Joerg Heyer,Maria I. Chiu,Richard Nicoletti
申请号:
US13455972
公开号:
US20120302572A1
申请日:
2012.04.25
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides diagnostic methods for assessing the EMT status of tumor cells, and for predicting the effectiveness of treatment of a cancer patient with an EGFR or IGF-1R kinase inhibitor, utilizing an EMT gene signature index score. The present invention further provides methods for treating patients with cancer that incorporate these methods.