Jeremy Clark;Cecil D. Kwong;Feng Geng;Abh;Anita T. Fowler;Joseph A. Maddry;Robert C. Reynolds;Subramaniam Ananthan;John J. Piwinski;Ashok Arasappan;F. George Njoroge;Frank Bennett;Hollis S. Kezar, III
发明人:
Cecil D. Kwong,F. George Njoroge,Subramaniam Ananthan,Ashok Arasappan,Frank Bennett,Jeremy Clark,Anita T. Fowler,Feng Geng,Hollis S. Kezar, III,Joseph A. Maddry,John J. Piwinski,Robert C. Reynolds,Abh
申请号：
US13059195
公开号：
US20120107271A1
申请日:
2009.08.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides compounds of Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and pro-drugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.
