Cecil D. Kwong,F. George Njoroge,Subramaniam Ananthan,Jeremy Clark,Feng Geng,Hollis S. Kezar, III,Joseph A. Maddry,John J. Piwinski,Robert C. Reynolds,Abhijit Roychowdhury,John A. Secrist, III,Neng-Ya
申请号：
US13059199
公开号：
US08715638B2
申请日:
2009.08.19
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides compounds of Formula (A): (Chemical formula should be inserted here as it appears on abstract in paper form) (A) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19, R22, R23, and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.
