Composition (I) comprises a combination of at least one monosaccharide comprising mannose, and/or rhamnose, and at least one additional compound comprising adenosine and/or one of its analogs in a medium. An independent claim is included for device comprising at least the combination of at least one monosaccharide and additional compound, where the device is adapted for intraepidermal and/or intradermal and/or subcutaneous injection. ACTIVITY : Dermatological Endocrine-Gen. MECHANISM OF ACTION : Pro-collagen I synthesis stimulator. Tests details are described but no results given.La présente invention concerne une composition notamment cosmétique et/ou dermatologique, comprenant dans un milieu physiologiquement acceptable, lassociation dau moins un monosaccharide choisi parmi le mannose, le rhamnose et leur mélange, et dau moins un composé additionnel choisi parmi ladénosine, un de ses analogues et leur mélange.