HMG-COA還原酶抑制劑和法尼基焦磷酸酶合成酶抑制劑的組合用於治療與異戊二烯基化的蛋白的持續存在和/或積累相關的疾病

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专利权人:

Universite dAix Marseille

发明人:

LEVY, Nicolas,CAU, Pierre,LOPEZ-OTIN, Carlos

申请号：

HK16103013.9

公开号：

HK1214965A

申请日:

2016.03.15

申请国别(地区):

HK

年份:

2016

代理人:

摘要：

The invention relates to the use of a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor and of a farnesyl-pyrophosphate synthase inhibitor, or of one of their associated physiologically acceptable salts, in the preparation of a composition, particularly a pharmaceutical composition, for use in the treatment of human or animal, pathological or nonpathological situations related to the accumulation and/or the persistence of prenylated proteins in cells, such as during progeria (Hutchinson-Gilford syndrome), restrictive dermopathy or physiological aging.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/