POHLMANN, JENS,BENJAMIN, DON GARY,MORONI, CHRISTOPH
申请号：
CA2878605
公开号：
CA2878605A1
申请日:
2013.07.03
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention relates to novel Rauwolfia alkaloid derivatives of formula (I) combinations of Rauwolfia alkaloid derivatives and a mitochondrial inhibitor, e.g. metformin, and the use of Rauwolfia alkaloid derivatives in combination with mitochondrial inhibitor for the treatment of cancer and for achieving clinical immunosuppression. The invention also relates to a fluorescence-based method for predicting the sensitivity of a cancer cell towards a compound of formula (I).
