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Nanoparticles Containing a Taxane and Their Use
专利权人:
ANP Technologies, Inc.;Fulgent Therapeutics, Inc.
发明人:
Ray Yin,Jing Pan,Yubei Zhang,Bingsen Zhou,Yun Yen
申请号:
US16578204
公开号:
US20200188315A1
申请日:
2019.09.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Symmetrically and asymmetrically branched homopolymers are modified at the surface level with functional groups that enable forming aggregates with a taxane, such as, paclilaxei and its derivatives, which are water insoluble or poorly water soluble. The aggregates are formed by interaction of a taxane and a homopolymer. Such aggregates improve drug solubility, stability, delivery and efficacy.
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