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NANOPARTICULES CONTENANT UN TAXANE ET LEUR UTILISATION
专利权人:
INC.;ANP TECHNOLOGIES;ANP TECHNOLOGIES, INC.;FULGENT THERAPEUTICS, INC.
发明人:
YIN, RAY,PAN, JING,ZHANG, YUBEI,ZHOU, BINGSEN,YEN, YUN
申请号:
EP14749276
公开号:
EP2953648A4
申请日:
2014.02.01
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Symmetrically and asymmetrically branched homopolymers are modified at the surface level with functional groups that enable forming aggregates with a taxane, such as, paclilaxei and its derivatives, which are water insoluble or poorly water soluble. The aggregates are formed by interaction of a taxane and a homopolymer. Such aggregates improve drug solubility, stability, delivery and efficacy.
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