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ADMINISTRATION OF INGENOL MEBUTATE
专利权人:
发明人:
Steven Martin Ogbourne
申请号:
US15351042
公开号:
US20170119719A1
申请日:
2016.11.14
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to novel crystalline forms of ingenol ingenol-3-angelate and methods of preparation and use thereof. More specifically, the invention relates to a novel crystalline form and purified forms of the compound of Formula 1 (ingenol-3-mebutate ingenol-3-angelate isoform ‘b’ PEP005), which is characterized by, for example, attenuated total reflectance Fourier transform infrared (FTIR-ATR) spectroscopy, single crystal X-Ray crystallography (XRC), X-ray powder diffraction, and, Differential Scanning calorimetry (DSC), and methods of preparation and use thereof.
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