作為吲哚胺2,3-二加氧酶和/或色胺酸2,3-二加氧酶選擇性抑制劑的新穎的5或8-取代的咪唑並[1,5-a]吡啶农业专利-农业学术服务平台

发明人:: WANG, HEXIANG,王鹤翔,王鶴翔,ZHANG, GUOLIANG,张国良,張國良,GUO, YUNHANG,郭运行,郭運行,REN, BO,任博,WANG, ZHIWEI,王　志伟,王　志偉,ZHOU, CHANGYOU,周　昌友,王志伟,王志偉,周昌友

摘要：: Disclosed herein are 5 or 8-substituted imidazo[1,5-a]pyridines and pharmaceutical compositions comprising at least one such 5 or 8-substituted imidazo[1,5-a]pyridines, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain 5 or 8-substituted imidazo[1,5-a]pyridines that can be useful for inhibiting indoleamine 2,3-dioxygenase and/or tryptophane 2,3-dioxygenase and for treating diseases or disorders mediated thereby.本申請公開了5或8-取代的咪唑並[1,5-a]吡啶和包含至少一種上述5或8-取代的咪唑並[1,5-a]吡啶的醫藥組合物、它們的製備方法，以及它們在治療中的用途。本申請公開了可用於抑制吲哚胺2,3-二加氧酶和/或色胺酸2,3-二加氧酶並治療由其介導的疾病或病症的某些5或8-取代的咪唑並[1,5-a]吡啶。