DERIVES D'INDOLE ET INDOLINE CYCLOPROPYL AMIDE COMME ANTAGONISTES DU RECEPTEUR EP4

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专利权人:

MERCK FROSST CANADA LTD.

发明人:

BOYD, MICHAEL,COLUCCI, JOHN,HAN, YONGXIN

申请号：

CA2679175

公开号：

CA2679175C

申请日:

2008.02.22

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The invention is directed to indole and indoline cyclopropyl amidederivatives of Formula I as EP4 receptor antagonists useful for the treatmentof EP4mediated diseases or conditions, such as acute and chronic pain,osteoarthritis, rheumatoidarthritis and cancer. Pharmaceutical compositions and methods of use are alsoincluded.(see formula I)

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