KERCHER TIMOTHY,ALLEN SHELLEY,JIANG YUTONG,WINSKI SHANNON L.,BRANDHUBER BARBARA J.,ANDREWS STEVEN WADE,BLAKE JAMES F.,HASS JULIA,KOLAKOWSKY GABRIELLE R.,THOMAS ALLEN A.
申请号：
CL2015001282
公开号：
CL2015001282A1
申请日:
2015.05.12
申请国别(地区):
CL
年份:
2015
代理人:
摘要：
or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.LA SOLICITUD SE REFIERE A COMPUESTOS DERIVADOS DE BICICLOS UNIDOS A UN GRUPO TIOUREA, UREA, GUANIDINA O CIANOGUANIDINA, INHIBIDORES TRKA, A UNA COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE, A UN PROCESO DE PREPARACIÓN Y A SU USO EN EL TRATAMIENTO DEL DOLOR, CÁNCER, INFLAMACIÓN, ENFERMEDADES NEURODEGENERATIVAS, INFECCIOSAS, ENTRE OTRAS
