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PHARMACEUTICAL COMPOSITIONS OF GHRH ANALOGS AND USES THEREOF
专利权人:
Theratechnologies Inc.
发明人:
Christian Marsolais,Kirill Shingel,Diane Potvin
申请号:
US16361990
公开号:
US20200297817A1
申请日:
2019.03.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A pharmaceutical composition comprising a GHRH molecule or a pharmaceutically acceptable salt thereof is described, as well as uses thereof and a kit for preparing such a pharmaceutical composition. In an embodiment, GHRH molecule or pharmaceutically acceptable salt thereof is trans-3-hexenoyl-GHRH(1-44)-NH2 or a pharmaceutically acceptable salt thereof. In an embodiment, a pharmaceutical composition comprising about 1.3 to about 1.5 mg of a GHRH molecule such as trans-3-hexenoyl-GHRH(1-44)-NH2 at a concentration of about 3.5 mg/mL or more, as well as uses thereof and a kit for preparing such a pharmaceutical composition, are described. Uses of such a pharmaceutical composition to obtain plasmatic levels of e.g., trans-3-hexenoyl-GHRH(1-44)-NH2 that are bioequivalent to administration of 2 mg of trans-3-hexenoyl-GHRH(1-44)-NH2 at a concentration of 1 mg/mL in a subject are also described.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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