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COMPOSITIONS PHARMACEUTIQUES D`ANALOGUES D`HORMONES DE LIBERATION DE L`HORMONE DE CROISSANCE (GHRH) ET LEURS UTILISATIONS
专利权人:
THERATECHNOLOGIES INC.
发明人:
MARSOLAIS, CHRISTIAN,SHINGEL, KIRILL
申请号:
CA3037757
公开号:
CA3037757A1
申请日:
2019.03.22
申请国别(地区):
CA
年份:
2020
代理人:
摘要:
A pharmaceutical composition comprising a GHRH molecule or a pharmaceuticallyacceptablesalt thereof is described, as well as uses thereof and a kit for preparingsuch a pharmaceuticalcomposition. In an embodiment, GHRH molecule or pharmaceutically acceptablesalt thereof istrans-3-hexenoyl-GHRH(1-44)-NH2 or a pharmaceutically acceptable salt thereof.In anembodiment, a pharmaceutical composition comprising about 1.3 to about 1.5 mgof a GHRHmolecule such as trans-3-hexenoyl-GHRH(1-44)-NH2 at a concentration of about3.5 mg/mL ormore, as well as uses thereof and a kit for preparing such a pharmaceuticalcomposition, aredescribed. Uses of such a pharmaceutical composition to obtain plasmaticlevels of e.g.,trans-3-hexenoyl-GHRH(1-44)-NH2 that are bioequivalent to administration of 2mg oftrans-3-hexenoyl-GHRH(1-44)-NH2 at a concentration of 1 mg/mL in a subject arealso described.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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