BAHULEKAR, RAMAN,MOSES, ARIKHA,BUEVICH, FATIMA,PULAPURA, SATISH,MCJAMES, WILLIAM C.
申请号：
CA2764134
公开号：
CA2764134C
申请日:
2010.06.01
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention generally relates to compositions and methods for preventingsternal wound infections, such as mediastinitis.In certain embodiments, the invention provides an antimicrobial compositionincluding at least one bioresorbable polymer,such as a tyrosine-derived polyesteramide, and at least one antimicrobialagent, in which the composition is adapted to betopically applied to an esophageal perforation in a subject or a mediansternotomy incision site in the subject, and in which the atleast one antimicrobial agent is present in an amount effective to inhibitdevelopment of mediastinitis in the subject.
