To provide a novel technology that can promote the production of interleukin-6, and to provide a novel technology that can promote the production of interleukin-10. Provided are an interleukin-6 production promoter that comprises a crude yeast cell wall hydrolysate, and an interleukin-10 production promoter that comprises a crude yeast cell wall hydrolysate.本發明的目的在於提供一種新穎的技術,其能夠促進介白素-6的生成。又,本發明的目的在於提供一種新穎的技術,其能夠促進介白素-10的生成。作為解決手段,是下述技術:一種介白素-6生成促進劑,其包含未精製的酵母細胞壁水解物;及,一種介白素-10生成促進劑,其包含未精製的酵母細胞壁水解物。