An apparatus (10) for controlling flow of fluid from a wound site of a patient may include a chamber (28) connectable to a wound site and a reservoir (16). The chamber (28) may have a first deformed state, and a second state in which it is not deformed or less deformed than in the first state. The chamber (28) may be adapted to manage fluid flow between the wound site and the reservoir (16) during transition of the chamber (28) between the first state and the second state. An actuator element (64) of the apparatus (10) may be adapted to operate on the chamber (28) to transition the chamber (28) from the second state to the first state.