Beth Israel Deaconess Medical Center, Inc.;Children's Medical Center Corporation
发明人:
Harrison, Stephen C.,Chen, Bing,Barouch, Dan H.,Nikolola, Joseph P.,Seaman, Michael Scott
申请号:
ES18150843
公开号:
ES2765890T3
申请日:
2009.10.13
申请国别(地区):
ES
年份:
2020
代理人:
摘要:
Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.