Beth Israel Deaconess Medical Center, Inc.;Children's Medical Center Corporation
发明人:
Stephen C. HARRISON,Bing CHEN,Dan BAROUCH,Joseph P. NKOLOLA,Michael Scott SEAMAN
申请号:
US16579025
公开号:
US20200023056A1
申请日:
2019.09.23
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.