PROBLEM TO BE SOLVED: To provide a blood purification device that stably performs concentration measurement of a waste product in drainage of a dialysate fluid to understand a therapeutic effect and a treatment state of a patient at a desired level of accuracy without a complicated device configuration.SOLUTION: A blood purification device 1 has a blood circuit 10, a second dialysis solution supply circuit 91, a first dialysis solution discharge circuit 92, and a water removal circuit 12. The water removal circuit 12 has: a storage container 151, which can stores the drainage in the dialysis solution a water removal pump 152, which pressure feeds the drainage in the storage container 151 to a downstream side at a predetermined flow rate a concentration sensor 153, which measures a concentration of a predetermined component of the drainage drained from the storage container 151 by the water removal pump 152 and an opening/closing valve 150, which adjusts the flow rate of the drainage on an upstream side of the storage container 151.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2016,JPO&INPIT【課題】血液浄化装置による患者の治療効果や治療状態を把握するための透析液の排液中の老廃物の濃度測定を、装置構成を複雑化することなく、所望の精度で安定的に行う。【解決手段】血液浄化装置1は、血液回路10と、第2の透析液供給回路91と、第1の透析液排出回路92と、除水回路12とを有している。除水回路12は、透析液の排液を貯留可能な貯留容器151と、貯留容器151の排液を所定の流量で下流側に圧送する除水ポンプ152と、除水ポンプ152により貯留容器151から排出された排液の所定成分の濃度を測定する濃度センサ153と、貯留容器151の上流側の排液の流量を調整する開閉バルブ150と、を有している。【選択図】図1