Tatiana Byzova,Ganapati H. Mahabaleshwar,Weiyi Feng
申请号：
US14937289
公开号：
US09592269B2
申请日:
2015.11.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A pharmaceutical composition includes a synthetic peptide consisting of about 10 to about 50 amino acids and having an amino acid sequence substantially homologous to consecutive amino acids of a portion of the cytoplasmic domain of at least one of αvβ3 integrin or VEGFR2 that includes a tyrosine residue, the amino acid sequence of the peptide including a phosphorylated tyrosine residue or a γ-carboxyglutamic acid residue that is substituted for a corresponding tyrosine residue of the portion of the cytoplasmic domain of αvβ3 integrin or VEGFR2.
