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Solid dosage forms of bendamustine
专利权人:
Astellas Deutschland GmbH
发明人:
Colledge, Jeffrey,Profitlich, Thomas Alfred,Patzak, Ulrich,Ouatas, Taoufik,Olthoff, Margaretha
申请号:
AU2009321728
公开号:
AU2009321728B2
申请日:
2009.12.03
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
In the present invention there is provided a pharmaceutical composition in a solid dosage form suitable for oral administration, the composition comprising bendamustine or a pharmaceutically acceptable ester, salt or solvate thereof as an active ingredient, and at least one pharmaceutically acceptable excipient, which is a pharmaceutically acceptable saccharide selected from the group consisting of one or more of a monosaccharide, a disaccharide, an oligosaccharide, a cyclic oligosaccharide, a polysaccharide and a saccharide alcohol, wherein the ratio by weight of the active ingredient to the saccharide excipient(s) is in the range of 1 :1-5.
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