Anatoly J. Nikolaev,Julie Pinkston-Gosse,Marc Tessier-Lavigne
申请号：
US13202144
公开号：
US20120076785A1
申请日:
2010.02.17
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Methods for screening for compounds that inhibit neurodegeneration are presented. Shedding of APP can be a useful marker for neurodegeneration and compounds that inhibit shedding of APP are useful as inhibitors of neurodegeneration. Such compounds may be useful in treatment and/or prevention of various neurological diseases, disorders and neuronal damage and may enhance growth, regeneration or survival of mammalian neuronal cells or tissue.
